Lactate clearance can be used to predict survival in patients with cardiogenic shock and aid in management decisions, and experts are calling for establishing lactate clearance as a standardized, ...

Background Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic ...

Some past studies have shown that the biomarkers PD-1 and PD-L1 are associated with response to ICI treatment in NSCLC as well as PFS and OS. Authors of past studies have also suggested that ...

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to ...

In clinical practice, lactate is a well-established tool for establishing diagnosis and prognosis in critically ill patients. 1 It can be used to diagnose sepsis and can also help in monitoring ...

For a long time, muscular fatigue during exercise was believed to be caused primarily by lactate as a by-product of glycolysis (glucose metabolism). In early studies, lactate was shown to increase in ...

A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical ...

Dynamic angiogenic switch as predictor of response to chemotherapy+ bevacizumab in patients with metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I.